Entamoeba histolytica-secreted products degrade colonic mucin oligosaccharides.
نویسندگان
چکیده
Degradation of the mucus layer by Entamoeba histolytica is a prerequisite for invasion of the colonic mucosa. In this study, we demonstrate that amoeba-secreted products degrade (3)H-labeled and native colonic mucin oligosaccharides independently of proteolytic activity. We conclude that E. histolytica degrades mucin oligosaccharides, which may facilitate parasite invasion of the colon.
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ورودعنوان ژورنال:
- Infection and immunity
دوره 73 6 شماره
صفحات -
تاریخ انتشار 2005